FDA and CDC Booster Vaccine Update

On 8/12 and 8/13/2021 the FDA and CDC recommended that an additional 3rd vaccine dose be given now for certain immunocompromised patients previously vaccinated with the Pfizer or Moderna vaccine.  

On 8/17/2021 the Biden administration announced that all vaccinated individuals should receive a booster dose 8 months after their first vaccine course.

From our study of over 1000 patients AOCC has identified certain drugs that may prevent one from developing an antibody response to the first vaccine course and could also be problematic when you receive the 3rd or booster dose.

  • If you have already had an antibody test performed by your provider at AOCC and had a negative response (no antibodies detected):
    •  talk with your provider about potential changes to your medication dosing or timing before proceeding with the 3rd vaccine dose.
    • Two weeks after getting the vaccine we should test you again to see if you responded to the vaccine.
  • If you have NOT had an antibody test and you are on Rituxan, Truxima, Orencia, Cellcept, mycophenylate orprednisone in doses greater than 10 mg a day
    • you should have an antibody test here before proceeding with the 3rd vaccine dose.
    • if the antibody test is negative , talk with your provider about potential changes to your medication dosing or timing before proceeding with the 3rd vaccine dose.
    • Two weeks after getting the vaccine we should test you again to see if you responded to the vaccine.
  • Some patients on Rituxan or Truxima will need to demonstrate a change in their B cell counts before a 3rd vaccine dose would even work. Talk to your provider about this.
  • Some patients on Cellcept/mycophenylate or iv Orencia may require changes in dosing and timing of drug in relationship to a 3rd vaccine dose. Talk to your provider about this.
  • Currently, patients who are immunocompromised because of the medication they are on can “self-identify” as being immunocompromised and do not require a note from their provider to receive the 3rdvaccine dose.
    • You need to wait at least 28 days from the time of your first vaccine course (2nd dose) before getting the 3rd
    • If you received the Pfizer vaccine initially you should be able to receive the 3rd dose using  either  the Pfizer or Moderna vaccine
    • If you received the Moderna vaccine initially  you should be able to receive the 3rd  dose using either the Moderna or the Pfizer vaccine
    • This program does NOT currently allow for an additional vaccine dose for those who received the Johnson & Johnson vaccine.
  • All other patients who have been previously vaccinated including those who received the Johnson and Johnson vaccine should soon be able to receive a booster dose of the vaccine if it has been 8 months from the time you received the first vaccine course.
  • Please refer to the AOCC website for further updates as well as listings of hospitals, county health departments and pharmacies that are offering COVID19 vaccines

Information Regarding The COVID-19 Vaccine Booster

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